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DCU has provided services for over 30 clinical studies, mostly involving multiple centers, and has acted as the coordinating center for a number of federally and industry funded projects.

The followings are some examples of major projects.

ALFSG NetworkOngoingNIDDKLiver failureI-III13 
APHASIAOngoingNICDRStrokeII274
CIS-PDOngoingMJFFPDI450
CREST2OngoingMayo ClinicCarotid StenosisIII~1202480
DEEP-TMSOngoingIndustryDepressionII4~50
DEFUSE3OngoingNINDSAcute Ischemic Anterior Circulation StrokeIII50476
EPISODOngoingNIDDKSODIII8314
ESETTOngoingNINDSBenzodiazipine Refractory Status EpilepticusIII~100795
FRAMESOngoingNIDDKPancreatitisII642
GAMES - RPOngoingIndustryIschemic StrokeII850
iDEFOngoingNINDSICHII40294
LARGEOngoingIndustryAneurysmIII~20316
LIVE-C-FreeOngoingMUSCHCVIII5230
NETT NetworkOngoingNINDSNeurological EmergenciesIII18 hubs 
PhoenixOngoingIndustryDepressionIII680
POINTOngoingNINDSTIA and minor ISIII~1005000
POLAROngoingNIDCDAphasiaII2150
PRIDEOngoingNIMHDepressionIII7250
PRoTECTOngoingNINDSTBIIII~401140
SHINEOngoingNINDSIschemic StrokeIII~1201400
Sister-to-SisterOngoingNIHSmokingIII2350
SLISSEOngoingNIDCDStrokeI/II150
STOP-ALFOngoingNIDDKLiver failureIIa624
StrokeNETOngoingNINDSStroke 25 RCCs 
SVIOngoingNIDDKPost-ERCP PancreatitisIII101430
TeleRehabOngoingNINDSStrokeII12124
ALIAS Part 1CompletedNINDSIschemic StrokeIII~100~500
ALIAS Part 2CompletedNINDSIschemic StrokeIII~1001500
ALISAHCompletedNINDSSAHII580
Amyotrophic Lateral Sclerosis (ALS)CompletedIndustry  8107
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