Valerie Durkalski, MPH, PhD, is a Professor of Biostatistics in the Department of Public Health Sciences at the Medical University of South Carolina (MUSC) and the Director of The Data Coordination Unit. She received her M.P.H. from Emory University (1996) and her Ph.D. in Biostatistics from MUSC (2001). As Director of the DCU, she collaborates on several large multicenter clinical trials in various therapeutic areas and has published and presented on various topics related to the design and conduct of multicenter trials. Currently, she is co-PI of the Statistical and Data Management Center (SDMC) for the NINDS sponsored Neurological Emergencies Treatment Trial Network (The NETT Network) and PI of the SDMC for the NIDDK sponsored Acute Liver Failure Study Group (ALFSG). In addition to these roles, Dr. Durkalski has research interests in non-inferiority trials as well as the implementation and analysis of adaptive trial designs.